register

News & Trends - Pharmaceuticals

Roche extends add-on evidence in breast cancer

Health Industry Hub | February 19, 2021 |
[Total: 1    Average: 5/5]

Pharma News: Findings from 6 years median follow-up in the APHINITY study confirm benefit in invasive disease-free survival (IDFS) from adding Roche’s Perjeta (pertuzumab) to standard adjuvant treatment in patients with node-positive, human epidermal growth factor receptor 2 (HER2)-positive early breast cancer.

The authors concluded that the second interim analysis of OS in the APHINITY study did not demonstrate a statistically significant OS benefit from adding Perjeta (pertuzumab) to standard chemotherapy plus Herceptin (trastuzumab) in HER2-positive early-stage breast cancer (p = 0.17); the number of OS events still remains relatively low.

The benefits of dual HER2 blockade using Perjeta (pertuzumab) and trastuzumab in the adjuvant setting for patients with node-positive disease observed at the primary analysis are reinforced in the updated analysis of IDFS. There is no evidence to justify the routine use of adjuvant dual anti-HER2 treatment for patients with node-negative early breast cancer.

Informa Telehealth Summit - Health Industry Hub supporting partner

Cardiac safety was confirmed with primary cardiac events remain <1% in both treatment groups.

The authors underlined that continued follow-up of patients is important to fully assess OS benefit at the time-driven third interim OS analysis planned for 2022.

To directly combat launch of biosimilar Herceptin, Roche in mid-2020 launched Phesgo, a fixed-dose combination of Herceptin and Perjeta, for HER2-positive breast cancer. The single-dose vial can be given in a treatment centre or at home, offering patients significant convenience. Previously, the two drugs had to be given separately. Phesgo is currently approved by the FDA and EMA, and awaiting TGA approval.


About the author

About the author

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nam luctus finibus scelerisque. Nunc bibendum ipsum sed augue fringilla fringilla. Nullam at consectetur leo. Praesent viverra rutrum porta. Quisque vitae mi vel purus vulputate tincidunt. Class aptent taciti sociosqu ad litora torquent per conubia nostra, per inceptos himenaeos. Suspendisse et mi quis nisi rhoncus feugiat at ac tellus. Sed aliquam sodales nulla ac auctor. Sed pretium lobortis purus accumsan ullamcorper. Phasellus sodales vel odio in lobortis. Duis maximus sagittis bibendum. Interdum et malesuada fames ac ante ipsum primis in faucibus. Nunc dictum tincidunt ipsum in vestibulum. Donec ut sem consectetur, aliquam quam vitae, pharetra orci. Nam egestas non velit eu rhoncus. Duis congue neque non lacus tincidunt porta. Vestibulum ultricies pulvinar sem, molestie congue dui aliquet non.
  • Ut imperdiet leo id lorem fermentum consectetur.
  • Ut vitae orci et dui varius tincidunt.
  • Ut id magna non libero vestibulum pharetra ac faucibus nulla.
Aliquam erat volutpat. Vestibulum vitae varius diam. Nulla eget congue ante. Nunc ullamcorper sagittis augue vel dictum. Mauris finibus nibh ut pulvinar auctor. Vestibulum ut faucibus nisi. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Quisque porta tortor ac justo malesuada elementum. Nulla tellus ante, cursus nec ex sit amet, suscipit bibendum arcu. Duis posuere orci dui, et mollis enim dictum at. Sed ullamcorper, sapien ut vulputate viverra, sem purus porttitor tellus, nec mattis mauris ligula sed risus. Nulla sagittis id ipsum eu mattis. Link to full profile

News & Trends - Medical Technology

MedTech News - Johnson & Johnson breaking down barriers to gender equality

Johnson & Johnson breaking down barriers to gender equality

Health Industry Hub | February 26, 2021 |

MedTech News: The Johnson & Johnson Family of Companies in Australia is pleased to announce that the company has been […]

More


Human Resources

Human Resource Management - National gender pay gap drops to 13.4%

National gender pay gap drops to 13.4%

Health Industry Hub | February 26, 2021 |

Human Resources: The Workplace Gender Equality Agency announced today that that national gender pay gap has dropped to 13.4%, a decline […]

More


News & Trends - Medical Technology

MedTech News - Philips one of first MedTechs to become carbon neutral

Philips, one of first MedTechs to become carbon neutral

Health Industry Hub | February 26, 2021 |

MedTech News: Philips Healthcare Australia, a global leader in health technology, has successfully met all the targets set out in […]

More


Social Responsibility

Social Responsibility and Community Engagement - The race to win the 2021 Medicines Australia, Kosi Pharma-Cup

The race to win the 2021 Medicines Australia Kosi Pharma-Cup

Health Industry Hub | February 26, 2021 |

The countdown is on for Rare Cancer Australia’s Kosi Challenge and the battle to win the Pharma-Cup sponsored by Medicines […]

More