register

News & Trends - Pharmaceuticals

Experts urge action to cut diagnostic delays in deadliest cancer affecting young adults

Health Industry Hub | May 30, 2024 |

Early-onset colorectal cancer (bowel cancer), diagnosed in individuals younger than 50, is on the rise, with critical warning signs often overlooked, leading to delays in diagnosis.

An international systematic review and meta-analysis involving nearly 25 million patients from 81 studies identified the most common symptoms of early-onset bowel cancer. These include blood in the stool (hematochezia), abdominal pain, altered bowel habits, and unexplained weight loss.

“In Australia, the risk of diagnosis with bowel cancer before age 40 has more than doubled since 2000, and knowing the symptoms is only part of the solution,” said Bowel Cancer Australia Medical Director, A/Prof Graham Newstead AM.

The study found that blood in the stool and abdominal pain were significantly associated with early-onset bowel cancer, with likelihoods increased by 5 to 54-fold and 1.3 to 6-fold, respectively.

“This latest study sends a clear message to GPs and younger people of the need to have a high suspicion of red flag signs and symptoms and to work together to ensure prompt access to colonoscopy to rule out early-onset bowel cancer as an underlying cause or to improve outcomes,” added A/Prof Newstead.

The researchers recommend that GPs implement a follow-up visit within 30 to 60 days for younger patients to confirm the initial diagnosis, check if the symptoms persist, or refer for a colonoscopy to exclude early-onset bowel cancer.

“Regardless of age, blood in the stool must be investigated for possible underlying bowel cancer,” A/Prof Newstead emphasised.

The analysis also highlighted that diagnostic delays are common, with the time from symptom onset to bowel cancer diagnosis ranging from 1.8 to 13.7 months, averaging 6.4 months. These delays are up to 40% longer for younger patients compared to older individuals, potentially leading to more late-stage diagnoses and higher mortality rates.

Supporting recent Australian research, the systematic review and meta-analysis revealed that younger people see multiple doctors over three months to five years before receiving a diagnosis. They make ten or more GP visits, with diagnostic times up to 60% longer than older patients, often resulting in later-stage diagnoses.

Early-onset bowel cancer is increasingly prevalent both in Australia and globally and is the deadliest cancer for individuals aged 25-44.

In reimagining healthcare across the entire patient journey, Health Industry HubTM is the ONLY one-stop-hub bringing the diversity of Pharma, MedTech, Diagnostics & Biotech sectors together to inspire meaningful change.

The exclusive leadership and influencer podcasts and vodcasts add huge value to our breaking news coverage. The content on Health Industry Hub is copyright protected and should only be accessed under individual user licenses. Please click here to subscribe and visit T&Cs here.


News & Trends - Pharmaceuticals

Clinicians unveil Novartis and BMS practice-changing trial results

Clinicians unveil Novartis and BMS practice-changing trial results

Health Industry Hub | June 24, 2024 |

Pharma News: Australia, known for its alarming melanoma rates, witnesses one person diagnosed with the disease every 30 minutes, and […]

More


News & Trends - Pharmaceuticals

Hearts4heart leads awareness week, amid progress in Boehringer Ingelheim and AstraZeneca therapies

Hearts4heart leads awareness week, amid progress in Boehringer Ingelheim and AstraZeneca therapies

Health Industry Hub | June 24, 2024 |

Pharma News: Heart failure is a significant health concern in Australia, affecting approximately half a million people, with over 67,000 […]

More


News & Trends - MedTech & Diagnostics

Cardiologists mark Australian first with Boston Scientific's intracoronary imaging system

Cardiologists mark Australian first with Boston Scientific’s intracoronary imaging system

Health Industry Hub | June 24, 2024 |

MedTech & Diagnostics News: Percutaneous coronary intervention (PCI) has faced substantial complications and failure rates, despite advances in medical devices […]

More


Leadership & Management

AbbVie New Zealand welcomes new leadership amid global moves

AbbVie New Zealand welcomes new leadership amid global moves

Health Industry Hub | June 24, 2024 |

Leadership & Management: In line with its global talent development plan, AbbVie has announced a significant change in leadership for […]

More


This content is copyright protected. Please subscribe to gain access.