register

News & Trends - Pharmaceuticals

AbbVie, Pfizer and Bayer therapies to be considered at upcoming PBAC intracycle meeting

Health Industry Hub | May 6, 2024 |

Pharma News: Therapies from AbbVie, Pfizer and Bayer are due to be considered at the Pharmaceutical Benefits Advisory Committee (PBAC) Intracycle Meeting Agenda in May.

AbbVie’s combination therapy Vyalev (foscarbidopa/foslevodopa), the first-and-only subcutaneous 24-hour infusion for advanced Parkinson’s Disease, was TGA approved in March and is now being considered for a positive PBAC recommendation in this patient cohort.

As Parkinson’s progresses, oral treatment options may no longer control symptoms appropriately. While Abbvie’s Duopa (carbidopa/levodopa) comes in a gel form and is administered orally with a pump through a stomach tube, Vyalev is given subcutaneously via a pump. Before starting Duopa, surgery is required to place the tube in the patient’s intestine, and some doctors may view the process as cumbersome.

In a randomised phase 3 trial, Vyalev significantly increased patients’ “on” time without dyskinesia (involuntary movements) compared with Duopa at week 12. The increase in “on” time was 2.72 hours for Vyalev versus 0.96 hours for the control arm.

Bayer is seeking a positive PBAC recommendation for Eylea (aflibercept) in diabetic macular oedema (DMO) and subfoveal choroidal neovascularisation (CNV) secondary to age-related macular degeneration.

Last month, data from Bayer’s PHOTON trial showed that a high-dose formulation of intravitreal Eylea (8 mg) in comparison to the lower dose (2mg) demonstrated non-inferior best-corrected visual acuity (BCVA) gains and similar safety profile with extended dosing intervals and could decrease treatment burden in patients with DMO.

In Australia, no respiratory syncytial virus (RSV) vaccines are currently funded under the National Immunisation Program (NIP). Pfizer’s resubmission for Abrysvo is being considered for NIP listing in prevention of lower respiratory tract disease caused by RSV in infants from birth through to 6 months. This follows the recent funding among NSW, QLD and WA state governments of Sanofi’s RSV vaccine for infants, Beyfortus (nirsevimab).

RSV currently stands as the leading cause of hospitalisations for children under five across the nation, with an average of 12,000 hospitalisations among infants each year.

In reimagining healthcare across the entire patient journey, Health Industry HubTM is the ONLY one-stop-hub bringing the diversity of Pharma, MedTech, Diagnostics & Biotech sectors together to inspire meaningful change.

The exclusive leadership and influencer podcasts and vodcasts add huge value to our breaking news coverage. The content on Health Industry Hub is copyright protected and should only be accessed under individual user licenses. Please click here to subscribe and visit T&Cs here.


Human Resources

The return-to-office debate: Where are we in the pendulum's swing?

The return-to-office debate: Where are we in the pendulum’s swing?

Health Industry Hub | May 24, 2024 |

People & Culture: The evolution of hybrid and flexible workplaces has yielded mixed results across the healthcare sector, with some […]

More


News & Trends - MedTech & Diagnostics

Cardinal Health launches local facility for reprocessing of single-use medical devices

Cardinal Health launches local facility for reprocessing of single-use medical devices

Health Industry Hub | May 24, 2024 |

MedTech & Diagnostics News: Cardinal Health is set to launch a cutting-edge facility in Australia dedicated to the reprocessing of […]

More


Medical

New ophthalmic centre to partner on pharma and medtech clinical trials

New ophthalmic centre to partner on pharma and medtech clinical trials

Health Industry Hub | May 24, 2024 |

Medical: The Victorian Deputy Premier and Minister for Medical Research, the Hon Ben Carroll, has launched a cutting-edge ophthalmic clinical […]

More


News & Trends - Pharmaceuticals

Private sector, government and academia gather to tackle barriers in vaccine value chain

Private sector, government and academia gather to tackle barriers in vaccine value chain

Health Industry Hub | May 24, 2024 |

Pharma News: An ‘invite only’ vaccine thought leadership event, aimed at addressing gaps in Australia’s vaccine ecosystem and maximising the […]

More


This content is copyright protected. Please subscribe to gain access.