Dance Biopharm partners with DarioHealth to expand access to digital therapeutics in chronic disease

Dance Biopharm, a clinical-stage company reimagining the treatment of chronic diseases with inhaled therapies, announced it has formed a strategic alliance with DarioHealth, a leading, global digital therapeutics company, to expand access to a personalised digital health management platform for patients with chronic diseases.

Under the terms of the agreement, Dance Biopharm will integrate its gentle mist smart inhaler into DarioHealth’s digital therapeutics platform to provide patients automated, real-time treatment data through an advanced mobile application. Dario will immediately start the design of the integrated solution for Dance to accommodate clinical trials and, upon regulatory approval, any marketed solutions.

Dance Biopharm’s smart inhaler paired with proprietary gentle mist biologic formulations allows for optimal and precise delivery of therapies through the lungs. The vibrating mesh within the device facilitates the transmission of a soft mist that allows for a lung deposition 2-4 times higher than conventional inhalers. In clinical trials, the device delivered a gentle mist formulation of human insulin with a faster drug onset and comparable duration to subcutaneous delivery of a rapid insulin (Humalog) in patients with type 2 diabetes (T2D). Dance is also advancing a convenient inhalable pre-meal GLP-1 receptor agonist to improve postprandial glucose control in T2D patients.

Dario’s digital therapeutics platform combines data analytics, high-quality software and personalised coaching to empower individuals with information to make healthy behavioral changes. The user-centric platform is comprised of MyDario, a mobile application that is data-driven, with an all-in-one blood glucose monitoring system and an optional connected blood pressure monitoring system. It is complemented by DarioEngage, a healthcare solutions platform for health and wellness providers to customise and integrate a patient’s data into their care continuum.

“We are excited to partner with DarioHealth in empowering patients to take charge of their chronic illness. This platform is well established in the digital therapeutics space and has demonstrated positive behavior change in patients with chronic diseases through its user-centered approach,” said Anne Whitaker, chief executive officer of Dance Biopharm. “We share a similar goal of adapting our platforms to chronic diseases beyond diabetes. Dance Biopharm is exploring opportunities to pair the smart inhaler with gentle mist biologic formulations beyond insulin. Our initial focus is on rare and severe diseases in the endocrinology, respiratory, and cardiovascular space, where our platform and expertise present a unique opportunity to achieve better treatment efficiency.”

“Diabetes is a complex chronic condition that evolves over time, making real-time, streamed patient data essential to care,” said Erez Raphael, chief executive officer of DarioHealth. “Through this strategic alliance, we are excited to expand the potential for our patient-centered, diabetes care and management solutions by integrating the smart inhaler, optimised to deliver a gentle mist formulation of insulin through the lungs, into our digital therapeutics platform, which includes blood glucose and blood pressure monitoring systems. Our goal is to place control of diabetes management directly into the hands of our users and, pending completion of clinical trials and regulatory approval, we believe that this alliance will help advance that critical objective.”

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