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News & Trends - MedTech & Diagnostics

A game-changer for renal disease diagnosis: NSW Health Pathology

Health Industry Hub | August 21, 2024 |

NSW Health Pathology’s Concord laboratory is celebrating the arrival of a new electron microscope, to the tune of $700,000, which will help pathologists and scientists more easily and effectively diagnose renal disease.

Clinical Director, Assoc Professor Charles Chan said electron microscopy plays an essential role in the diagnosis of kidney diseases.

“The electron microscope transmits a beam of electrons through ultrathin sections of tissue specimens to produce high-resolution magnified images. With its integrated high-resolution camera, it can “see” with 1,000 to 100,000 times magnification which allows it to look at extremely small structures,” A/Prof Chan said.

“It allows us to take a look inside cells and their surroundings in a kidney biopsy at high magnification and see exactly what the pathologic defect is and its specific location – which means a more definitive diagnosis and treatment options for renal disease patients.”

The Electron Microscopy Unit at Concord Hospital is our statewide referral service for electron microscopy and is the largest diagnostic service of its kind in Australia. NSW Health Pathology labs at Liverpool and Westmead also support this vital statewide service. At Concord, we receive specimens from across NSW and ACT as well as many internationally from New Zealand, New Caledonia and Fiji.

“The highly skilled team processes and report approximately 2,200 cases annually and this number is growing by over nine per cent each year against a background of increased chronic diseases in the population. In fact, our workload has more than doubled over the last 10 years,” A/Prof Chan said.

“The use of electron microscopy has evolved over the years, with advancing medical knowledge and the changing incidence of diseases. The ability of the electron microscope to identify minute structural changes within and around abnormal cells makes it a powerful technique to characterise and diagnose an increasing number of newly recognised diseases,” he said.

Concord now has two electron microscopes, which allows for improved workflow and more efficient turnaround times of diagnoses.

“With two electron microscopes, scientists/pathologists can view cases simultaneously, which will improve our overall turnaround times,” he said. “We will also be able to continue working and reporting cases in the event that one instrument is undergoing routine maintenance or repair.”

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