register

News & Trends - Pharmaceuticals

20 biopharmaceutical companies enter a ground-breaking partnership

Health Industry Hub | July 13, 2020 |

Pharma News: More than 20 leading biopharmaceutical companies announced the launch of the AMR Action Fund, a ground-breaking partnership that aims to bring 2-4 new antibiotics to patients by 2030.

These treatments are urgently needed to address the rapid rise of antibiotic-resistant infections – also called antimicrobial resistance, or AMR. The companies have raised so far nearly US$1 billion new funding to support clinical research of innovative new antibiotics that are addressing the most resistant bacteria and life-threatening infections.

Through the AMR Action Fund, pharmaceutical companies will join forces with philanthropies, development banks, and multilateral organisations to strengthen and accelerate antibiotic development. The Fund will focus on urgent public health needs.  It will provide much needed financial resources, as well as important technical support to help biotech companies bring novel antibiotics to patients.

AMR is a looming global crisis that has the potential to dwarf COVID-19 in terms of deaths and economic costs. While tragically the death toll of COVID-19 continues to rise, each year 700,000 people are dying from AMR. In some of the most alarming scenarios, it is estimated that by 2050 AMR could claim as many as 10 million lives per year.

“Unlike COVID-19, AMR is a predictable and preventable crisis. We must act together to rebuild the pipeline and ensure that the most promising and innovative antibiotics make it from the lab to patients,” said Thomas Cueni, Director General of the IFPMA, one of the organisers of the new fund. He adds “The AMR Action Fund is one of the largest and most ambitious collaborative initiatives ever undertaken by the pharmaceutical industry to respond to a global public health threat”.

The world urgently needs new antibiotics, but there are few in the pipeline because of a paradox: despite the huge societal costs of AMR, there is currently no viable market for new antibiotics. New antibiotics are used sparingly to preserve effectiveness, so in recent years, a number of antibiotic-focused biotechs have declared bankruptcy or exited this space due to the lack of commercial sustainability, resulting in the loss of valuable expertise and resources. The consequence is a huge public health need for new antibiotics, but a lack of funding available for antibiotic R&D, particularly the later stages of clinical research. This creates a “valley of death” between discovery and patient access. 

“With the AMR Action Fund, the pharmaceutical industry is investing nearly US$1 billion to sustain an antibiotic pipeline that is on the verge of collapse, a potentially devastating situation that could affect millions of people around the world,” said David Ricks, Chairman and CEO of Eli Lilly and Company and President of IFPMA. “The AMR Action Fund will support innovative antibiotic candidates through the most challenging later stages of drug development, ultimately providing governments time to make the necessary policy reforms to enable a sustainable antibiotic pipeline.”

“AMR is a slow tsunami that threatens to undo a century of medical progress. I very much welcome this new engagement of the private sector in the development of urgently-needed antibacterial treatments. WHO looks forward to working with the AMR Action Fund to accelerate research to address this public health crisis.” Dr Tedros Adhanom Ghebreyesus, Director General World Health Organisation

While the AMR Action Fund is an important step in addressing the challenge of AMR, policymakers across the globe must enact market-based reforms, including reimbursement reform and new pull incentives, to revitalize the antibiotics market and drive sustainable investments in antibiotic R&D. Until then, the biopharmaceutical industry is taking action now to support the current pipeline of antibiotics.

With this investment from leading biopharmaceutical companies, the AMR Action Fund will be the largest collective venture ever created to address AMR. The AMR Action Fund will:

  1. Invest in smaller biotech companies focused on developing innovative antibacterial treatments that address the highest priority public health needs, make a significant difference in clinical practice, and save lives.
  2. Provide technical support to portfolio companies, giving them access to the deep expertise and resources of large biopharmaceutical companies, to strengthen antibiotic development, and support access and appropriate use of antibiotics.
  3. Bring together a broad alliance of industry and non-industry stakeholders, including philanthropies, development banks, and multilateral organisations, and help encourage governments to create market conditions that enable sustainable investment in the antibiotic pipeline.

The AMR Action Fund expects to invest more than US$1 billion with the support of future partners into a portfolio of companies to address the funding gap for the financing of antibiotic development. The Fund is expected to be operational during the fourth quarter of 2020.

Biopharmaceutical companies and foundations supporting the AMR Action Fund

Almirall, Amgen, Bayer, Boehringer Ingelheim, Chugai, Daiichi Sankyo, Eisai, Eli Lilly and Company, GlaxoSmithKline, Johnson & Johnson, LEO Pharma, Lundbeck, Menarini, Merck, MSD, Novartis, Novo Nordisk, Novo Nordisk Foundation, Pfizer, Roche, Shionogi, Takeda, Teva, UCB


News & Trends - Pharmaceuticals

Sanofi's departing Country Lead leaves three-decade legacy of strategic, compassionate leadership

Sanofi’s departing Country Lead leaves three-decade legacy of strategic, compassionate leadership

Health Industry Hub | April 17, 2024 |

Pharma News: In a significant development for Sanofi’s local operations, Karen Hood, a seasoned leader with 28 years of invaluable […]

More


Human Resources

AbbVie appoints new HR Director with diverse expertise across healthcare

AbbVie appoints new HR Director with diverse expertise across healthcare

Health Industry Hub | April 17, 2024 |

AbbVie has appointed a new Human Resources Director for Australia and New Zealand. Ally Jonas assumed the role earlier this […]

More


Digital & Innovation

Department of Health hits milestone in digital transformation

Department of Health hits milestone in digital transformation

Health Industry Hub | April 17, 2024 |

Digital & Innovation: The Department of Health and Aged Care has reached the midpoint of its digital transformation journey. While […]

More


News & Trends - Pharmaceuticals

Paradigm-changing outcomes for patients with acute myeloid leukaemia

Paradigm-changing outcomes for patients with acute myeloid leukaemia

Health Industry Hub | April 17, 2024 |

Pharma News: Australian researchers have found a new combination treatment to treat a form of leukaemia that prolongs remission. A […]

More


This content is copyright protected. Please subscribe to gain access.